PRICE: $12.95 for each 60 capsule bottle (1/2 gram per capsule) Barlowe's Herbal Elixirs brings you the ultimate Ashwagandha extract. This is a potent extract which has been standardized to 1.7% Withanolides. Click on this link: Ashwagandha Extract COA, to see the Certificate of Analysis on this particular batch. Ashwagandha, oftentimes called "Indian Ginseng," is an exotic Indian ayurvedic herb and powerful adaptogen which has remarkable stress-relieving properties. These capsules are filled by hand with a manual encapsulation machine, not with a high speed automatic machine, and thus, only pure, unadulterated Ashwagandha 1.7% Extract is in the capsules. Capsules produced with high speed machines in herbal remedy and vitamin "factories" contain several other ingredients, including preservatives because so many bottles of product are produced at one time, and lubricants to ensure that the machines will run faster and more efficiently. Check their labels! Also, Barlowe's Herbal Elixirs is one of the very few manufacturers that still pack their products in glass whenever possible, even though glass is more expensive. Barlowe believes that chemicals can leach out of plastic containers and contaminate the contents, and that the use of glass is much better for the environment. Ashwagandha has been utilized in Indian medicine for thousands of years. It is used in ayurvedic medicine similarly to how ginseng is used in traditional Chinese medicine. In Ayurveda, Ashwaganda is considered a rasayana herb which works on a nonspecific basis to increase health and longevity, and it is oftentimes used to increase sexual potency in both men and women. In addition to its excellent protective effects on the nervous system, studies have shown that Ashwagandha may be a promising alternative treatment for a variety of degenerative diseases such as Alzheimer’s and Parkinson’s. Ashwagandha has powerful antioxidant properties against the free radicals that have been implicated in aging and numerous other disease states. Also, studies suggest that Ashwagandha has anti-cancer benefits as well. Ashwagandha has been demonstrated to be as effective as some tranquilizers and antidepressant drugs. Oral administration of Ashwagandha for five days suggested anxiety-relieving effects similar to those achieved by anti-anxiety drugs, and anti-depressant effects similar to those of antidepressant drugs. Bhattacharya SK, Bhattacharya A, Sairam K, Ghosal S., Anxiolytic-antidepressant activity of Withania somnifera glycowithanolides: an experimental study. Phytomedicine. 2000 Dec;7(6):463-9. Also, the premature aging associated with chronic nervous tension may be related to increased oxidative stress, which is abolished by the potent antioxidant properties of ashwagandha extract. Studies on chronic stress support this hypothesis. In a remarkable animal study, examination of the brains showed that 85% of the brain cells observed in test animals exposed to chronic stress showed signs of degradation. It is this type of cellular degradation that can lead to long-term cognitive difficulties. Amazingly, when Ashwagandha was administered to chronically stressed animals, the number of degraded brain cells was reduced by 80%. Jain S, Shukla SD, Sharma K, Bhatnagar M., Neuroprotective effects of Withania somnifera in hippocampal sub-regions of female albino rat. Phytother Res. 2001 Sep;15(6):544-8. The Institute of Natural Medicine at the Toyama Medical and Pharmaceutical University in Japan has also conducted extensive research into the brain benefits of Ashwagandha extract. The Institute’s scientists were studying ways to regenerate brain nerve cell components called axons and dendrites. Researchers noted that Ashwagandha caused significant regeneration of the axons and dendrites of nerve cells, and supported the reconstruction of synapses - junctions where nerve cells communicate with other cells. The scientists concluded that Ashwagandha extract helps to reconstruct networks of the nervous system, making it a potential treatment for neuro and age-related degenerative diseases such as Alzheimer’s. Kuboyama T, Tohda C, Komatsu K., Neuritic regeneration and synaptic reconstruction induced by withanolide A. Br J Pharmacol. 2005 Apr;144(7):961-71. The same scientists also found that Ashwagandha extract supported the growth of nerve cell dendrites, indicating that Ashwagandha might help treat dementia, (Tohda C, Kuboyama T, Komatsu K., Dendrite extension by methanol extract of Ashwagandha (roots of Withania somnifera) in SK-N-SH cells. Neuroreport. 2000 Jun 26;11(9):1981-5), and that it also promoted the growth of heathy nerve cells. Tohda C, Kuboyama T, Komatsu K., Search for natural products related to regeneration of the neuronal network. Neurosignals. 2005;14(1-2):34-45. Ashwagandha also shows promise as a treatment for Parkinson’s and Alzheimer’s diseases. In a recent study, Ashwagandha extract reversed neurodegeneration similar to that found in Parkinson's disease significantly. Ahmad M, Saleem S, Ahmad AS, et al, Neuroprotective effects of Withania somnifera on 6-hydroxydopamine induced Parkinsonism in rats. Hum Exp Toxicol. 2005 Mar;24(3):137-47. An earlier study demonstrated that Ashwagandha extract inhibits acetylcholinesterase, an enzyme responsible for breaking down one of the brain’s key chemical messengers. Drugs currently used to slow the progression of Alzheimer’s disease act similarly. Choudhary MI, Yousuf S, Nawaz SA, Ahmed S, Atta UR., Cholinesterase inhibiting withanolides from Withania somnifera. Chem Pharm Bull (Tokyo). 2004 Nov;52(11):1358-61. Recent evidence suggests that Ashwagandha also has impressive cancer fighting abilities. Studies show that Ashwagandha extract inhibits the growth of human breast, lung, and colon cancer cell lines in the laboratory. This inhibition was comparable to that achieved with some common cancer chemotherapy drugs. In fact, researchers reported that Withaferin A, a compound extracted from Ashwagandha, was more effective than Doxorubicin in inhibiting breast and colon cancer cell growth. Jayaprakasam B, Zhang Y, Seeram NP, Nair MG., Growth inhibition of human tumor cell lines by withanolides from Withania somnifera leaves. Life Sci. 2003 Nov 21;74(1):125-32. A recent study showed that Ashwagandha inhibits a cancer cell's ability to reproduce, and also helps prevents the cancer from forming new blood vessels. Mathur R, Gupta SK, Singh N, et al, Evaluation of the effect of Withania somnifera root extracts on cell cycle and angiogenesis. J Ethnopharmacol. 2006 Jan 9. Ashwagandha extract taken orally has also been shown to inhibit both stomach and skin cancers. Padmavathi B, Rath PC, Rao AR, Singh RP, Roots of Withania somnifera inhibit forestomach and skin carcinogenesis in mice. Evid Based Complement Alternat Med. 2005 Mar;2(1):99-105; Mathur S, Kaur P, Sharma M, et al, The treatment of skin carcinoma, induced by UV B radiation, using 1-oxo-5beta, 6beta-epoxy-witha-2-enolide, isolated from the roots of Withania somnifera, in a rat model. Phytomedicine. 2004 Jul;11(5):452-60. Based on the above, it is clear that Ashwagandha has impressive and powerful properties, especially against the problems associated with stress. Indeed, it appears to be the ultimate adaptogen - a good indication of why it has been used for thousands of years in India to treat a variety of illnesses. Barlowe's Herbal Elixirs recommends that Ashwagandha should play a part in everyone's diet. Caution: Barlowe's Ashwagandha Extract uses only the finest quality Ashwagandha 1.7% Standardized Extract from the most trusted suppliers. This superb tonic and adaptogenic herb is generally safe, but it is potent and should be utilized with care. This product is for dietary use. If side-effects occur, discontinue use immediately! The above statements have not been evaluated by the Food and Drug Administration (FDA). This product is not intended to diagnose, treat, cure, or prevent any disease. Directions For Use: Take one (1/2 gram) capsule either once or twice a day. Results and usage amounts may vary based on body type and weight. Ashwagandha Extract 1.7% Withanolides Standardized PRICE: $12.95 for each 60 capsule bottle (1/2 gram per capsule)
PRICE: $12.95 for each 60 capsule bottle (1/2 gram per capsule)
Barlowe's Herbal Elixirs brings you the ultimate Ashwagandha extract. This is a potent extract which has been standardized to 1.7% Withanolides. Click on this link: Ashwagandha Extract COA, to see the Certificate of Analysis on this particular batch. Ashwagandha, oftentimes called "Indian Ginseng," is an exotic Indian ayurvedic herb and powerful adaptogen which has remarkable stress-relieving properties. These capsules are filled by hand with a manual encapsulation machine, not with a high speed automatic machine, and thus, only pure, unadulterated Ashwagandha 1.7% Extract is in the capsules. Capsules produced with high speed machines in herbal remedy and vitamin "factories" contain several other ingredients, including preservatives because so many bottles of product are produced at one time, and lubricants to ensure that the machines will run faster and more efficiently. Check their labels! Also, Barlowe's Herbal Elixirs is one of the very few manufacturers that still pack their products in glass whenever possible, even though glass is more expensive. Barlowe believes that chemicals can leach out of plastic containers and contaminate the contents, and that the use of glass is much better for the environment.
Ashwagandha has been utilized in Indian medicine for thousands of years. It is used in ayurvedic medicine similarly to how ginseng is used in traditional Chinese medicine. In Ayurveda, Ashwaganda is considered a rasayana herb which works on a nonspecific basis to increase health and longevity, and it is oftentimes used to increase sexual potency in both men and women. In addition to its excellent protective effects on the nervous system, studies have shown that Ashwagandha may be a promising alternative treatment for a variety of degenerative diseases such as Alzheimer’s and Parkinson’s. Ashwagandha has powerful antioxidant properties against the free radicals that have been implicated in aging and numerous other disease states. Also, studies suggest that Ashwagandha has anti-cancer benefits as well.
Ashwagandha has been demonstrated to be as effective as some tranquilizers and antidepressant drugs. Oral administration of Ashwagandha for five days suggested anxiety-relieving effects similar to those achieved by anti-anxiety drugs, and anti-depressant effects similar to those of antidepressant drugs. Bhattacharya SK, Bhattacharya A, Sairam K, Ghosal S., Anxiolytic-antidepressant activity of Withania somnifera glycowithanolides: an experimental study. Phytomedicine. 2000 Dec;7(6):463-9. Also, the premature aging associated with chronic nervous tension may be related to increased oxidative stress, which is abolished by the potent antioxidant properties of ashwagandha extract. Studies on chronic stress support this hypothesis. In a remarkable animal study, examination of the brains showed that 85% of the brain cells observed in test animals exposed to chronic stress showed signs of degradation. It is this type of cellular degradation that can lead to long-term cognitive difficulties. Amazingly, when Ashwagandha was administered to chronically stressed animals, the number of degraded brain cells was reduced by 80%. Jain S, Shukla SD, Sharma K, Bhatnagar M., Neuroprotective effects of Withania somnifera in hippocampal sub-regions of female albino rat. Phytother Res. 2001 Sep;15(6):544-8.
The Institute of Natural Medicine at the Toyama Medical and Pharmaceutical University in Japan has also conducted extensive research into the brain benefits of Ashwagandha extract. The Institute’s scientists were studying ways to regenerate brain nerve cell components called axons and dendrites. Researchers noted that Ashwagandha caused significant regeneration of the axons and dendrites of nerve cells, and supported the reconstruction of synapses - junctions where nerve cells communicate with other cells. The scientists concluded that Ashwagandha extract helps to reconstruct networks of the nervous system, making it a potential treatment for neuro and age-related degenerative diseases such as Alzheimer’s. Kuboyama T, Tohda C, Komatsu K., Neuritic regeneration and synaptic reconstruction induced by withanolide A. Br J Pharmacol. 2005 Apr;144(7):961-71. The same scientists also found that Ashwagandha extract supported the growth of nerve cell dendrites, indicating that Ashwagandha might help treat dementia, (Tohda C, Kuboyama T, Komatsu K., Dendrite extension by methanol extract of Ashwagandha (roots of Withania somnifera) in SK-N-SH cells. Neuroreport. 2000 Jun 26;11(9):1981-5), and that it also promoted the growth of heathy nerve cells. Tohda C, Kuboyama T, Komatsu K., Search for natural products related to regeneration of the neuronal network. Neurosignals. 2005;14(1-2):34-45.
Ashwagandha also shows promise as a treatment for Parkinson’s and Alzheimer’s diseases. In a recent study, Ashwagandha extract reversed neurodegeneration similar to that found in Parkinson's disease significantly. Ahmad M, Saleem S, Ahmad AS, et al, Neuroprotective effects of Withania somnifera on 6-hydroxydopamine induced Parkinsonism in rats. Hum Exp Toxicol. 2005 Mar;24(3):137-47. An earlier study demonstrated that Ashwagandha extract inhibits acetylcholinesterase, an enzyme responsible for breaking down one of the brain’s key chemical messengers. Drugs currently used to slow the progression of Alzheimer’s disease act similarly. Choudhary MI, Yousuf S, Nawaz SA, Ahmed S, Atta UR., Cholinesterase inhibiting withanolides from Withania somnifera. Chem Pharm Bull (Tokyo). 2004 Nov;52(11):1358-61.
Recent evidence suggests that Ashwagandha also has impressive cancer fighting abilities. Studies show that Ashwagandha extract inhibits the growth of human breast, lung, and colon cancer cell lines in the laboratory. This inhibition was comparable to that achieved with some common cancer chemotherapy drugs. In fact, researchers reported that Withaferin A, a compound extracted from Ashwagandha, was more effective than Doxorubicin in inhibiting breast and colon cancer cell growth. Jayaprakasam B, Zhang Y, Seeram NP, Nair MG., Growth inhibition of human tumor cell lines by withanolides from Withania somnifera leaves. Life Sci. 2003 Nov 21;74(1):125-32. A recent study showed that Ashwagandha inhibits a cancer cell's ability to reproduce, and also helps prevents the cancer from forming new blood vessels. Mathur R, Gupta SK, Singh N, et al, Evaluation of the effect of Withania somnifera root extracts on cell cycle and angiogenesis. J Ethnopharmacol. 2006 Jan 9. Ashwagandha extract taken orally has also been shown to inhibit both stomach and skin cancers. Padmavathi B, Rath PC, Rao AR, Singh RP, Roots of Withania somnifera inhibit forestomach and skin carcinogenesis in mice. Evid Based Complement Alternat Med. 2005 Mar;2(1):99-105; Mathur S, Kaur P, Sharma M, et al, The treatment of skin carcinoma, induced by UV B radiation, using 1-oxo-5beta, 6beta-epoxy-witha-2-enolide, isolated from the roots of Withania somnifera, in a rat model. Phytomedicine. 2004 Jul;11(5):452-60.
Based on the above, it is clear that Ashwagandha has impressive and powerful properties, especially against the problems associated with stress. Indeed, it appears to be the ultimate adaptogen - a good indication of why it has been used for thousands of years in India to treat a variety of illnesses. Barlowe's Herbal Elixirs recommends that Ashwagandha should play a part in everyone's diet.
Caution:
Barlowe's Ashwagandha Extract uses only the finest quality Ashwagandha 1.7% Standardized Extract from the most trusted suppliers. This superb tonic and adaptogenic herb is generally safe, but it is potent and should be utilized with care. This product is for dietary use. If side-effects occur, discontinue use immediately! The above statements have not been evaluated by the Food and Drug Administration (FDA). This product is not intended to diagnose, treat, cure, or prevent any disease.
Directions For Use:
Take one (1/2 gram) capsule either once or twice a day. Results and usage amounts may vary based on body type and weight.
Ashwagandha Extract 1.7% Withanolides Standardized
