Nettle High Potency Extract

Barlowe's Herbal Elixirs brings you the highest grade and most targeted Nettle High Potency Extract which has been specifically designed to increase free testosterone.  This is a potent extract which is generally called the 95% 3,4-divanillyltetrahydrofuran extract. Over the last few years there has been substantial discourse on the bodybuilding forums regarding whether or not this particular product is actually a 95% 3,4-divanillyltetrahydrofuran extract, or whether this is simply a highly concentrated ratio extract of nettle root. Barlowe's is making no specific claim regarding the exact breakdown of this Nettle Extract. Bottled in Glass! No Stearates! No Fillers! No Junk!

Each capsule now contains 350 milligrams of the 95% high potency nettle root extract. One capsule taken twice a day is the therapeutic dosage needed to optimally bind SHBG and increase free testosterone in someone of normal physical condition.  Although Nettle (Urtica dioica) has been utilized for hundreds of years to treat a variety of ailments, it is primarily of interest now because it has been discovered that it is able to increase free testosterone in the bloodstream, and 3,4-divanillyltetrahydrofuran is the substance in Nettle which primarily causes this effect.

***These vegetable-derived capsules (Vegan, Kosher and Halal certified) are filled on slow speed equipment and only pure, unadulterated herbal extract is contained in the capsules. There are no magnesium stearates, fillers, gelatin, silicates, gluten, corn, wheat, rice, yeast, starch, titanium dioxide, artificial colors, artificial flavors or preservatives. Capsules produced with high speed equipment in herbal and dietary supplement "factories" generally contain several other ingredients, including powdered lubricants called STEARATES (which can greatly diminish an herb or supplement's absorption into the body). Check their labels! Barlowe also bottles his products in glass as he believes chemical vapors can vent from plastic containers and contaminate the contents and that glass is better for the environment.

For many men, a safe and easy way to increase free testosterone is to prevent it from being converted (aromatized) into estrogen. Too much estrogen plays havoc with a man's sex life by binding to testosterone receptor sites and may contribute to the over-production of sex hormone-binding globulin (SHBG). SHBG binds free testosterone in a way that makes it unavailable to receptor sites in the brain, nerves and genitals. High serum levels of estrogen also trick the brain into thinking that enough testosterone is being produced, thereby slowing the natural production of testosterone. Some studies show that the decline in sexual interest with advancing age is not always due to the amount of testosterone produced, but rather to the increased binding of testosterone to globulin by SHBG. This explains why some older men who are on testosterone replacement therapy do not report a long-term aphrodisiac effect. The artificially administered testosterone becomes bound by SHBG, and is not available to cellular receptor sites where it would normally produce a libido-enhancing effect.

Logically, one way of increasing libido in older men would be to block the testosterone-binding effects of SHBG. This would leave more testosterone in its free, sexually activating form. A highly concentrated extract from the Nettle root provides a unique mechanism for increasing levels of free testosterone. Recent European research has identified constituents of Nettle root that bind to SHBG in place of testosterone, thus reducing SHBG's binding of free testosterone. Therefore, this product is an excellent herbal extract to take in combination with Barlowe's Tongkat Ali, Bulbine Natalensis, or Fenugreek Extracts, as the Tongkat, the Bulbine, and the Fenugreek dramatically increase level of testosterone, and the High Potency Nettle Extract keeps the raised testosterone in its free, powerful form.

ATTENTION: IF YOU HAVE ANY PRODUCT QUESTIONS, PLEASE CONTACT BARLOWE AT 954-479-4320. WE DO NOT ACCEPT PHONE ORDERS. SORRY.

Testimonials:

I thought you might like to know the results of a recent experiment with your high potency Nettle Root Extract. The background is that in recent years my levels of SHBG (sex hormone binding globulin) have soared considerably beyond the upper limit of the reference range, while my total and free testosterone have declined. After searching the scientific literature, I came across 3,4-DVTHF (3,4-divanillyltetrahydrofuran) as an effective means of lowering SHBG. Further research revealed that some suppliers have been selling products labeled as 3,4-DVTHF actually contained very little. I decided to take a chance on your product because you seem to be a reputable company and your label indicates a high content of purified 3,4-DVTHF per capsule.  After an initial purchase, I bought three bottles of Nettle Root Extract and took 3 capsules twice a day for one month before retesting for SHBG and testosterone. The results showed that my SHBG decreased by 16 nmol/L while my free and total testosterone increased by 1.31 and 11 ng/dL, respectively. While still not at the levels they once were, they nevertheless represent a considerable improvement. Congratulations on selling an honest and effective product! I have told several other people about my results and they are ordering as well. W.S., Arlington, MA (11/26/2018)

Research: 

Medical Uses of Nettle

Nettle's Use for BPH

Interaction of lignans with human sex hormone binding globulin (SHBG).
Schottner M, Gansser D, Spiteller G.
Lehrstuhl Organische Chemie I, Universitat Bayreuth, Germany.

Lignans bind to sex hormone-binding globulin (SHBG). The lignan with the highest binding affinity is (+/ )-3,4-divanillyltetrahydrofuran. In a double Stobbe condensation--without use of protecting groups--a wide variety of lignans with different substitution pattern in the aromatic and aliphatic part of the molecule was synthesized. These lignans were tested in a SHBG-binding assay which allowed to deduce the following relationship between structure and activity: 1) (+/-)-diastereoisomers are more active than meso compounds 2.) the 4-hydroxy-3-methoxy (guajacyl) substitution pattern in the aromatic part is most effective 3.) the activity increases with the decline in polarity of the aliphatic part of the molecule.

Lignans from the roots of Urtica dioica and their metabolites bind to human sex hormone binding globulin (SHBG).
Schottner M, Gansser D, Spiteller G.
Lehrstuhl Organische Chemie I, Universitat Bayreuth, Germany.

Polar extracts of the stinging nettle (Urtica dioica L.) roots contain the ligans (+)-neoolivil, (-) secoisolariciresinol, dehydrodiconiferyl alcohol, isolariciresinol, pinoresinol, and 3,4 divanillyltetrahydrofuran. These compounds were either isolated from Urtica roots, or obtained semisynthetically. Their affinity to human sex hormone binding globulin (SHBG) was tested in an in vitro assay. In addition, the main intestinal transformation products of plant lignans in humans, enterodiol and enterolactone, together with enterofuran were checked for their activity. All lignans except (-) pinoresinol developed a binding affinity to SHBG in the in vitro assay. The affinity of (-)-3,4 divanillyltetrahydrofuran was outstandingly high. These findings are discussed with respect to potential beneficial effects of plant lignans on benign prostatic hyperplasia (BPH).

Caution: This extract is generally safe, but it is potent and should be utilized with care. This product is for dietary use. If side-effects occur, discontinue use immediately! The above statements have not been evaluated by the Food and Drug Administration (FDA). This product is not intended to diagnose, treat, cure, or prevent any disease.

Directions For Use: As a dietary supplement, take one capsule twice a day without food. Results and usage amounts may vary based on body type and weight. Keep bottle tightly closed whenever possible as this product is quite hygroscopic and can easily absorb moisture from the air.

Nettle Root Super High Potency Extract        PRICE: $18.95 for each 60 capsule bottle (350 mg per vegi-capsule)